PhD position in bone research

The Department of Clinical Cell Biology at Vejle Hospital - Lillebaelt Hospital which is connected to the University of Southern Denmark is inviting applications from qualified candidates for a Ph.D. project of three years duration. The Department of Clinical Cell Biology is a bone research department consisting of twelve scientists biomedical laboratory technicians and Ph.D. students managed by Professor Jean-Marie Delaisse. The department aims to form a bridge between clinical and basic research in order to investigate the bone remodeling process as it occurs in humans. 

Bones are constantly renewed during adulthood in order to remain functional. This renewal process called bone remodeling involves bone resorption by osteoclasts bone formation by osteoblasts and an intermediate step called reversal phase which has received only very little attention until now. We identified recently two critical cellular players of the reversal phase: (i) osteoblast lineage cells which colonize the excavations vacated by the osteoclasts and that we called reversal cells; (ii) osteoblast lineage cells which line the bone marrow above bone remodelling sites and that we called bone remodelling compartment canopy cells. The aim of this project is to investigate the origin fate and activity of these two cell types especially in the context of the preparation to bone formation and of osteoblast differentiation. The project will be performed on human bone biopsy specimens and will include advanced histological procedures and analyses. A part of the project is expected to be performed at the laboratory facilities of our collaborators at the University of Aarhus.         
 
Candidate requirements
As a candidate we expect that you:

• have obtained a MSc  or MD degree 
• are a team-player
• are open and honest
• are ambitious and explorative
• are ready to work dedicated and focused on the project
• are well organized and take the responsibility for the success of the project

 
Approval and enrolment
The approval of the candidate and enrolment for the Ph.D. degree are subject to academic approval and the candidate will be enrolled in one of the Ph.D. schools at the University of Southern Denmark.
 
Salary and appointment terms
The salary and appointment terms are consistent with the current regional rules for Ph.D. degree students. The period of employment is three years and expected to be initiated the 1^st of august 2012. However the actual employment will first start when an official application for enrolment as a Ph.D. student has been submitted to the University of Southern Denmark.  
 
Supervisors

• Professor Jean-Marie Delaisse Head of the Dept. of Clinical Cell Biology tel.: +45 79406656
• Senior Scientist Thomas Levin Andersen Dept. of Clinical Cell Biology tel.: +45 79406654

Application
The application deadline is by the 1^st of June 2012. The application should include:

• a letter stating the motivation to apply for the application
• curriculum vitae
• recommendations and contact information on relevant contact persons for oral recommendation
• grade transcripts (translated to the Danish grading system) and a MSc or MD diploma.

Fagområde
Ph.d. stipendiat

Stillingsbetegnelse

Arbejdstid

Arbejdssted
Vejle

Ansøgningsfrist
01-06-2012

Sygehus Lillebælt består af sygehusene i Fredericia Give Kolding Middelfart og Vejle. Vi har en årsomsætning på 31 mia. kroner. Vi vægter udvikling forskningsaktivitet effektive pakkeforløb og patienttilfredshed højt og er flere gange kåret som Danmarks bedste hospital af Dagens Medicin.

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